Follistatin anticorps
Aperçu rapide pour Follistatin anticorps (ABIN636639)
Antigène
Voir toutes Follistatin (FST) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Purified
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Immunogène
- Follistatin antibody was raised in rabbit using highly pure recombinant human Follistatin as the immunogen.
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Indications d'application
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ELISA: 0.5-2 µg/mL, Inhibition: 8-12 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Follistatin (FST)
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Autre désignation
- Follistatin
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Sujet
- Follistatin is a secreted protein that binds to ligands of the TGF beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues.
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Poids moléculaire
- 31.5 kDa (predicted detection band MW)
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Pathways
- Negative Regulation of Hormone Secretion
Antigène
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